The Power of AI-Driven Automation in Cell Passaging and Expansion

Cell-based models are essential for drug development and biological research. However, traditional tissue culture remains one of the most labor-intensive and error-prone aspects of laboratory work. Complex protocols, sensitivity to handling errors, and the need for extensive training make it difficult to achieve reproducibility and quality control in manual cell culture processes.

This application note describes the use of the CellXpress.ai™ Automated Cell Culture System for automated AI-driven cell maintenance and expansion. In this work, the CellXpress.ai™ system was tasked with automatically triggering passage of HTC116 cell lines based on predefined cell density thresholds and without manual interaction.

By leveraging image-based analysis and automated decision-making, the CellXpress.ai system can significantly reduce hands-on time, while enhancing reproducibility and precise control of cell culture conditions.

Read the application note to learn more.